Single-use (disposable) technology is a proven alternative solution for the biopharmaceutical industry offering several significant advantages over standard reusable stainless steel systems, by reducing:

• Cross-contamination risk
• Cleaning and associated cleaning validation
• Capital investment
• Lead times
• The number of connections to enhance sterility assurance
  

Furthermore, in applications where hazardous materials are being processed, such as cytotoxic drugs or potent biological materials, closed single-use systems offer additional protection to operators who are isolated from these hazards.
Pall recognizes that single-use systems are becoming the technology of choice for a large number of applications in biopharmaceutical processing. We are focusing our resources on the production of innovative, single-use technologies to serve the market needs.
As a result Pall has the most comprehensive single-use product range to serve all applications from upstream through downstream as well as Filling and Formulation.

• Kleenpak™ sterile connectors that allow the sterile connection of two sterile entities in all types of environments;
• Allegro™ Biocontainers -  a large range of process bags with improved features for connection purposes and drainability;
• Capsule filters from very small Acrodisc® units to 30-inch Kleenpak™ Nova capsule filters with the widest range of filter media and connection capabilities;
• Tangential Flow Filtration devices in a variety of configurations to match application requirements: cassettes, Microza hollow fibers, and Kleenpak TFF capsules;
• Chromatography with single-use Mustang® chromatography capsules for capture and polishing applications.

Single-Use Systems Provide Flexibility
Pall Allegro™ systems provide a high degree of flexibility for your process design. They allow you to easily evaluate different configurations before agreeing on the final design. Then, should your batch size be modified, or your requirements evolve, your systems can be easily tailored to fit with your new requirements.
Our technology is applicable to a wide range of unit operations. There will always be at least one step of your process that can benefit from single-use technology.ją.

Technology Available at all Multiple Scales
Pall Allegro™ systems can be used at many scales, from the manufacturing of small, clinical batches to full production scale. Most components are now available at all scales: from capsule filters to chromatography capsules, bags and all related equipment. With consistent materials of construction from small to large scale, single-use systems are ideal for scaling up or scaling down your process.